Model year
2021 Mercedes-Benz E-Class
NHTSA does not list the EPA model name E-Class for 2021. Under the matched names AMG E53, AMG E63, AMG E63S, E 350, E 350 E, and E 450, NHTSA lists 19 recalls and 25 complaints (recall file dated Oct 23, 2026; complaint file dated Oct 23, 2026). The components listed on the most complaints for E 350 are ELECTRICAL SYSTEM (4), ENGINE (4), POWER TRAIN (3). NHTSA rated 4 variants 5 stars overall. EPA rates it 18–26 mpg combined depending on configuration (fuel economy file dated Sep 29, 2026). EPA's annual fuel-cost figures for these configurations are $3,150–$4,550, based on 15,000 miles and 55% city driving.
- 2000 34 complaints
- 2001 15 complaints
- 2002 8 complaints
- 2003 45 complaints
- 2004 15 complaints
- 2005 9 complaints
- 2006 10 complaints
- 2007 436 complaints
- 2008 5 complaints
- 2009 85 complaints
- 2010 258 complaints
- 2011 296 complaints
- 2012 235 complaints
- 2013 188 complaints
- 2014 304 complaints
- 2015 57 complaints
- 2016 89 complaints
- 2017 167 complaints
- 2018 71 complaints
- 2019 59 complaints
- 2020 24 complaints
- 2021 25 complaints
- 2022 23 complaints
- 2023 24 complaints
- 2024 12 complaints
- 2025 10 complaints
- 2026 6 complaints
- 2027 0 complaints
Matched NHTSA names
The EPA model name is not itself a name in the NHTSA file for 2021. The counts in the answer are the sum of the names below. Overlap between those names is not removed.
| NHTSA name | Recalls | Complaints | Investigations |
|---|---|---|---|
| AMG E53 | 15 | 5 | 0 |
| AMG E63 | 6 | 0 | 0 |
| AMG E63S | 4 | 0 | 0 |
| E 350 | 12 | 13 | 0 |
| E 350 E | 1 | 0 | 0 |
| E 450 | 14 | 7 | 0 |
Recalls for E 350
23V445000 · Jun 26, 2023
FUEL SYSTEM, GASOLINE:DELIVERY:FUEL PUMP
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.
22V365000 · May 20, 2022
COMMUNICATION: AUTO CRASH NOTIFICATION; ELECTRICAL SYSTEM:SOFTWARE
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles. Please refer to MBUSA's recall report for…
22V232000 · Apr 8, 2022
BACK OVER PREVENTION:DISPLAY FUNCTION
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2018-2021 CLA-Class, GLE/GLS-Class, A-Class, C-Class, E-Class, E-Class Coupe/Convertible, GLA/GLB-Class, GLC-Class, and CLS-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The rearview…
22V189000 · Mar 25, 2022
STEERING: STEERING WHEEL/HANDLE BAR
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel. Due to a software error in the hand detection control unit, the hands-off…
21V527000 · Jul 12, 2021
AIR BAGS:SENSOR:SIDE IMPACT
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 CLS450, AMG E53, AMG CLS53, E350, E450, AMG GT43, AMG GT53, 2020 S450, S560, G550, AMG GLC63, 2020-2021 GLC300, and AMG G63 vehicles. The side crash sensor connectors may come loose, which could delay the activation of…
21V483000 · Jun 25, 2021
SEAT BELTS:REAR/OTHER:RETRACTOR
Mercedes-Benz, LLC (MBUSA) is recalling certain 2021 G550, AMG G63, E350, E450, AMG CLS53, AMG E53, AMG GT43, AMG GT53, AMG GT63, 2021-2022 CLS450, and AMG E63 vehicles. The rear seat belt automatic locking retractors may deactivate early, which can prevent the child restraint…
21V354000 · May 14, 2021
BACK OVER PREVENTION: SENSING SYSTEM: CAMERA; ELECTRICAL SYSTEM:SOFTWARE
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2021 CLA-Class, GLE/GLS-Class, A-Class, E-Class, E-Class Coupe and Convertible, GLA/GLB-Class, GLC-Class, CLS-Class, and AMG GT-Class 4-door Coupe vehicles. Please refer to MBUSA's recall report for specific vehicle model…
21V230000 · Apr 1, 2021
SEAT BELTS:PRETENSIONER; AIR BAGS:SENSOR:OCCUPANT CLASSIFICATION; SEATS
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 C-Class, E-Class, E-Class Coupe and Convertible, GLC, CLS, AMG GT 4-door Coupe and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. A faulty electrical contact within the seat…
21V228000 · Apr 1, 2021
BACK OVER PREVENTION:WARNINGS:EXTERNAL/PEDESTRIAN ALERT; BACK OVER PREVENTION: SENSING SYSTEM: CAMERA
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 E350, E450, E450 Wagon, and AMG E63 vehicles. The parking control unit may fail to display the rearview camera image and cause the parking sensors to misidentify or fail to detect objects.
21V216000 · Mar 26, 2021
SEATS:FRONT ASSEMBLY:POWER ADJUST; SEATS
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 E350, E450, E450 Wagon, E63S AMG, 2020 E63S AMG Wagon, and 2020-2021 E53 AMG vehicles. The passenger seat limiter may allow the seat to be positioned too close to the air bag.
2 more recalls are in the NHTSA file for this name and are not listed here. Campaign numbers above link to NHTSA.
Complaints for E 350
13 distinct complaints. Crash flag on 0, fire flag on 1, injury field 0, deaths field 0. A complaint can be counted under more than one component. The injury and death figures are the file's numbers (the highest value on each complaint, then added), not a separate verified count of people.
Investigations for E 350
No investigations are matched to this name.
Safety ratings
| Variant | Overall | Front | Side | Pole | Rollover | Photo |
|---|---|---|---|---|---|---|
| 2DR 4WD | Not rated | Not Rated | Not Rated | Not Rated | Not Rated · possibility 0 | — |
| 2DR RWD | Not rated | Not Rated | Not Rated | Not Rated | Not Rated · possibility 0 | — |
| 4 DR 4WD | 5 | 5 | 5 | 5 | 5 · possibility 0.097 | NHTSA photo |
| 4 DR RWD | 5 | 5 | 5 | 5 | 5 · possibility 0.097 | NHTSA photo |
| Cabriolet C 4WD | Not rated | Not Rated | Not Rated | Not Rated | Not Rated · possibility 0 | — |
| Cabriolet C RWD | Not rated | Not Rated | Not Rated | Not Rated | Not Rated · possibility 0 | — |
| SW 4WD | 5 | 5 | 5 | 5 | 5 · possibility 0.097 | — |
| SW RWD | 5 | 5 | 5 | 5 | 5 · possibility 0.097 | — |
Fuel economy
| Configuration | Fuel | City | Hwy | Comb | kWh/100 mi | Range | Annual fuel cost |
|---|---|---|---|---|---|---|---|
| E350 · 2L · Automatic 9-spd · Rear-Wheel Drive | Premium Gasoline | 22 | 31 | 25 | — | — | $3,300 |
| E350 4matic · 2L · Automatic 9-spd · 4-Wheel Drive | Premium Gasoline | 22 | 30 | 25 | — | — | $3,300 |
| E450 4matic All-Terrain (wagon) · 3L · Automatic 9-spd · 4-Wheel Drive | Premium Gasoline · Hybrid | 22 | 28 | 24 | — | — | $3,400 |
| E450 4matic · 3L · Automatic 9-spd · 4-Wheel Drive | Premium Gasoline · Hybrid | 23 | 30 | 26 | — | — | $3,150 |
| AMG E53 4matic Plus Coupe · 3L · Automatic 9-spd · 4-Wheel Drive | Premium Gasoline · Hybrid | 21 | 28 | 24 | — | — | $3,400 |
| E450 Coupe · 3L · Automatic 9-spd · Rear-Wheel Drive | Premium Gasoline · Hybrid | 23 | 31 | 26 | — | — | $3,150 |
| E450 4matic Coupe · 3L · Automatic 9-spd · 4-Wheel Drive | Premium Gasoline · Hybrid | 23 | 30 | 25 | — | — | $3,300 |
| AMG E53 4matic Plus Convertible · 3L · Automatic 9-spd · 4-Wheel Drive | Premium Gasoline · Hybrid | 21 | 27 | 23 | — | — | $3,550 |
| E450 Convertible · 3L · Automatic 9-spd · Rear-Wheel Drive | Premium Gasoline · Hybrid | 23 | 30 | 25 | — | — | $3,300 |
| E450 4matic Convertible · 3L · Automatic 9-spd · 4-Wheel Drive | Premium Gasoline · Hybrid | 23 | 29 | 25 | — | — | $3,300 |
| AMG E53 4matic Plus · 3L · Automatic 9-spd · 4-Wheel Drive | Premium Gasoline · Hybrid | 22 | 29 | 25 | — | — | $3,300 |
| AMG E63 S 4matic Plus · 4L · Automatic 9-spd · 4-Wheel Drive | Premium Gasoline | 16 | 23 | 18 | — | — | $4,550 |
1 more configurations are in the EPA file and are not listed in this table. The fuel-cost calculator lists every configuration.
Open this model year in the fuel-cost calculator. The calculator starts with no fuel price filled in.
Check a vehicle
This page is not a VIN lookup. NHTSA's recall tool checks a specific vehicle: nhtsa.gov/recalls. NHTSA's page for this model year is 2021 Mercedes-Benz E-Class at NHTSA. Complaint narratives stay on NHTSA's site and are not copied here.